Ethyl gallate

CAS No. 831-61-8

Ethyl gallate ( —— )

Catalog No. M19155 CAS No. 831-61-8

Ethyl gallate obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG 38 In Stock
1G 59 In Stock

Biological Information

  • Product Name
    Ethyl gallate
  • Note
    Research use only, not for human use.
  • Brief Description
    Ethyl gallate obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner.
  • Description
    Ethyl gallate obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhibit the abilities of invasion of breast cancer in vitro by inhibiting the mRNA levels of MMP-9/MMP-2, phosphorylation of Akt and protein expression of NF-κB and inhibits hydrogen peroxide signaling, may represent an alternative class of vasopressors for use in septic shock. Also, Ethyl gallate suppresses proliferation and invasion in human breast cancer cells by modulating the PI3K/Akt pathway, which may contribute to inhibiting their downstream targets such as NF-κB p-65, Bcl-2/Bax, and mRNA levels of MMP-2 and MMP-9 in breast cancer cells, could be used as potential antioxidants with safe therapeutic application in cancer chemotherapy.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Akt; MMP-2; MMP-9; NF-κB
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    831-61-8
  • Formula Weight
    198.17
  • Molecular Formula
    C9H10O5
  • Purity
    98%
  • Solubility
    DMSO : 150 mg/mL 756.93 mM;
  • SMILES
    CCOC(=O)c1cc(c(c(c1)O)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cui H, et al. Oncol Rep. Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-κB signaling. 2015 Mar;33(3):1284-90.
molnova catalog
related products
  • Ethyl 34-dihydroxybe...

    Ethyl?34-dihydroxybenzoate?(EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.

  • CH5132799

    CH5132799 has been used in trials studying the treatment of Solid Tumors.

  • 2,3,4,6-Tetra-o-acet...

    2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.